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Tacrolimus, Tacrolimus Powder, Buy Tacrolimus manufacturer / supplier in China, offering High Purity Antibiotics Powder CAS 104987-11-3 Tacrolimus, Boldenone Undecylenate Liquid Equipoise EQ 300mg/Ml 200mg/Ml EQ 300, Factory Sale 95% Pharmaceutical Chemicals Raw Material Furacilin and so on.

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Supplier Homepage Product Health Care Supplements High Purity Antibiotics Powder CAS 104987-11-3 Tacrolimus

High Purity Antibiotics Powder CAS 104987-11-3 Tacrolimus

FOB Price: US $1 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1/ g
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Port: Shanghai, China
Production Capacity: 2000
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 104987-11-3
  • Customized: Customized
  • Suitable for: Elderly
  • Purity: >99%
  • CAS: 104987-11-3
  • Shipping: Safe
  • Transport Package: as You Requiry
  • Origin: China
  • Powder: Yes
  • Certification: ISO 9001, USP
  • State: Solid
  • Name: Tacrolimus
  • Sample: Free
  • Trademark: saichuang
  • Specification: 99%
  • HS Code: 3001200090
Product Description
Product name:Tacrolimus
Other Name:(2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide;
Original:China
CAS:104987-11-3
Molecular formula:C44H69NO12
MW:804.02
Brand nameNJBNSteroid
Leading timewithin 24 hours upon receipt of payment
DeliveryFast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity99%
PackageDiscreet and Hidden package according to specific requirement
AppearanceWhite crystal powder
CertificationSGS, ISO 9001, KOSHER
Payment TermsWestern Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity10g
PriceNegotiable
 
Description of Active Pharmaceutical Ingredients Tacrolimus :
 
1. Tacrolimus is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response.
 
2. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.
Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.
 
3. Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.
 
Medical Usage of Active Pharmaceutical Ingredients Tacrolimus:
 
Immunosuppression following transplantation:
 
It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long-term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate, and IL-2 receptor inhibitors such as basiliximab. Dosages are titrated to target blood levels.
 
Ulcerative colitis:
 
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis (UC), a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
 
Dermatological use:
 
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way tosteroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects.
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
 
Technical Testing Sheet of Active Pharmaceutical Ingredients Tacrolimus:
 
COA:
 
 
Test ItemsSpecificationResults
Identification (IR)Should match with working standardConfirms
Solubility Confirms
Melting point246.0~252.0ºC246.0ºC~248.0ºC
Water by KFNot more than 0.5%0.14%
Loss on dryingNot more than 0.5%0.17%
Residue on ignitionNot more than 0.2%0.05%
Heavy MetalsNot more than 20ppmConfirms
Single maximum impurityNot more than 0.5%0.34%
Total impuritiesNot more than 1.0%0.66%
Assay by HPLC98.0% -102.0%101.0%
Conclusionconforms with USP 32 Standard
 
How to Complete an Order
 
Make an order1.Please let me know the items you are looking for, quantity, and the destination country;
2.You confirm all details, and offer us purchasing order;
3.We send the detail price of our product and offer the suitable shipping method for reference;
4.You confirm the order and pay money 100% in advance and send us the detail address.
5.We arrange the shipment according to your requirements.
6.We offer after-sales service after you receive parcel.
ShippingProvide your addressee info. ( phone number , zip code )
PackingAccording to different countries and quantity of orders
Lead TimeArranged within 12 hours upon receipt of your payment
PhotosPhotos of parcel would be offered to tell apart the steroids in advance
Delivery TimeUsually 4-6 working days to reach destinations
Tracking numberOffered once it is released on the Net .Normally within 24hours upon the receipt of payment.
After-sale service24/7 online for problems and concern related to steroids
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